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  1. wijnand van den van den berg

    De relatie met persisterend foramen ovale zal wel weer niet worden meegenomen … Patent Foramen Ovale and Dementia
    In the US alone, 4.5 million people have been diagnosed with some degree of dementia. Purandare found that spontaneous cerebral emboli was present in 40 % of patients with Alzheimer’s and nearly 37 % of Alzheimer’s have a PFO.16 Purandare also explored the role of paradoxical embolization in dementia by investigating cerebral emboli, venous to arterial circulation shunts, and carotid artery disease. The results of the study showed that cerebral emboli were detected in 27 % of dementia patients compared with 7 % in the control group. In the dementia patients with cerebral emboli, a venous to arterial shunt was detected in 64 % and moderate to severe carotid stenosis was present in 30 %.17 These data confirm paradoxical embolization as a potential mechanism for cerebral damage, influencing vascular dementia and Alzheimer’s disease.

    • wijnand van den van den berg

      Bv onderzoek high risk population met ApoE4/ApoE4 Interventie sluiten pfo op bep leeftijd of desnoods pas bij aanvang klachten lijkt zinvol